Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 219.00 | |
5 mg | In stock | $ 438.00 | |
10 mg | In stock | $ 686.00 | |
25 mg | In stock | $ 1,070.00 | |
50 mg | In stock | $ 1,450.00 | |
100 mg | In stock | $ 1,950.00 |
Description | Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor. |
In vitro | The production of maleimidocaproyl-MMAE (mc-MMAE) involves introducing maleimidocaproic acid into a dichloromethane solution containing MMAE. This process is then followed by adding diethyl cyanophosphonate and diisopropylethylamine[1]. |
Synonyms | Maleimidocaproyl-monomethylauristatin E |
Molecular Weight | 911.18 |
Formula | C49H78N6O10 |
CAS No. | 863971-24-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 51 mg/mL (55.97 mM)
H2O: < 0.1 mg/mL (insoluble), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mc-MMAE 863971-24-8 Cytoskeletal Signaling Microtubule Associated Inhibitor Drug-Linker Conjugates for ADC McMMAE Microtubule/Tubulin Mc MMAE inhibit Maleimidocaproyl-monomethylauristatin E inhibitor