Powder: -20°C for 3 years
In solvent: -80°C for 2 years
ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
Description | ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4. |
Targets&IC50 | CXCR6:140 nM |
In vitro | The murine assay was validated using anti-mCXCR16 as an antagonist positive control tested in the presence of an EC80 concentration of mCXCL16 (IC50 = 1.5 nM; % response = 100%). Probe ML339 was shown to be 100-fold less active at the murine CXCR6 receptor using the DiscoveRx β-arrestin cell-based assay format[1]. |
Molecular Weight | 502 |
Formula | C26H32ClN3O5 |
CAS No. | 2579689-83-9 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 125 mg/mL (249.00 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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ML339 2579689-83-9 Autophagy GPCR/G Protein Immunology/Inflammation CXCR prostate cancer CXC chemokine receptors inhibit CXCR6 ML 339 Inhibitor ML-339 inhibitor