Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Lactacystin is an Antibiotic Streptomyces spp. the metabolite and is an effective and selective Proteasome inhibitor (IC50: 4.8 μM for 20S Proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A.
Description | Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A. |
Targets&IC50 | Proteasome:4.8 μM |
In vivo | After injection in young and adult mice, Lactacystin (microinjection; 2 μg) causes a Parkinson's disease-like motor phenotype 5-7 days [2]. |
Molecular Weight | 376.43 |
Formula | C15H24N2O7S |
CAS No. | 133343-34-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Lactacystin 133343-34-7 Proteases/Proteasome Ubiquitination Proteasome Inhibitor inhibitor inhibit