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LIMK-IN-22j

Name: LIMK-IN-22j
Brand: TargetMol
SKU: T24410
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T24410Cas No. 1116571-01-7

Alias LIMK inhibitor-22j, LIMK inhibitor 22j, LIMK IN 22j

LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.

LIMK-IN-22j

🥰Excellent

Purity: 99.165%

Catalog No. T24410Alias LIMK inhibitor-22j, LIMK inhibitor 22j, LIMK IN 22jCas No. 1116571-01-7

LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$41	In Stock
10 mg	$59	In Stock
25 mg	$107	In Stock
50 mg	$153	In Stock
1 mL x 10 mM (in DMSO)	$57	In Stock

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Batch Information

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Purity:99.165%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.
Targets&IC50	LIMK1:0.9 nM, LIMK2:0.5 nM, ROCK1:260 nM, ROCK2:2700 nM
Synonyms	LIMK inhibitor-22j, LIMK inhibitor 22j, LIMK IN 22j

Chemical Properties

Molecular Weight	453.34
Formula	C₂₀H₂₁BrN₈
Cas No.	1116571-01-7
Smiles	C[C@H]1CN(CCN1\C(Nc1cccc(Br)c1)=N\C#N)c1ncnc2[nH]cc(C)c12
Relative Density.	1.54 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (121.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2058 mL	11.0292 mL	22.0585 mL	110.2925 mL
5 mM	0.4412 mL	2.2058 mL	4.4117 mL	22.0585 mL
10 mM	0.2206 mL	1.1029 mL	2.2058 mL	11.0292 mL
20 mM	0.1103 mL	0.5515 mL	1.1029 mL	5.5146 mL
50 mM	0.0441 mL	0.2206 mL	0.4412 mL	2.2058 mL
100 mM	0.0221 mL	0.1103 mL	0.2206 mL	1.1029 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc