Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 159.00 | |
5 mg | In stock | $ 396.00 | |
10 mg | In stock | $ 589.00 | |
25 mg | In stock | $ 945.00 | |
50 mg | In stock | $ 1,280.00 | |
100 mg | In stock | $ 1,730.00 | |
500 mg | In stock | $ 3,460.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 446.00 |
Description | IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM. |
Targets&IC50 | Nurr1:3.9 nM(EC50) |
In vivo | IP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE)[1]. |
Synonyms | IP 7e, IP-7e, isoxazolo-pyridinone 7e |
Molecular Weight | 390.43 |
Formula | C23H22N2O4 |
CAS No. | 500164-74-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (243.32 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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IP7e 500164-74-9 Others inhibit IP 7e Inhibitor IP-7e orally Nurr1 NF-kB isoxazolo-pyridinone 7e brain-penetrant inhibitor