Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.
Description | HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol. |
In vitro | HOKU-81 was approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs. HOKU-81 appears to be a potent and selective beta 2-stimulant with a slight inotropic action. Adrenergic Receptor Effects of HOKU-81 on isolated trachea and atria of guinea pigs were compared with those of various bronchodilators. This effect of HOKU-81 seems to be due to direct action on the adrenergic beta-receptor. |
Synonyms | 4-Hydroxytulobuterol |
Molecular Weight | 243.73 |
Formula | C12H18ClNO2 |
CAS No. | 58020-43-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (205.15 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HOKU-81 58020-43-2 Others HOKU81 4-Hydroxytulobuterol HOKU 81 inhibitor inhibit