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Cycloolivil

Catalog No. T3839   CAS 3064-05-9
Synonyms: Isoolivil

Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees. Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base

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Cycloolivil Chemical Structure
Cycloolivil, CAS 3064-05-9
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees. Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base
In vitro Cycloolivil reduced the ability of thrombin to stimulate platelet aggregation. Cycloolivil reduced thrombin-evoked Ca(2+) release and entry to a similar extent to hydroxytyrosol. This effect was greater in platelets from patients with type 2 diabetes mellitus than in controls. Thrombin-, thapsigargin- and 2,5-di-(tert-butyl)-1,4-hydroquinone (TBHQ)-evoked protein tyrosine phosphorylation, which is involved in Ca(2+) signalling and platelet aggregation, is inhibited by Cycloolivil. Cycloolivil is a natural oxygen radical scavenger that reduces thrombin-induced protein tyrosine phosphorylation, Ca(2+) signalling and platelet aggregation[1].
Source
Synonyms Isoolivil
Molecular Weight 376.4
Formula C20H24O7
CAS No. 3064-05-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Zbidi H, et al. Olive tree wood phenolic compounds with human platelet antiaggregant properties. Blood Cells Mol Dis. 2009 May-Jun;42(3):279-85.

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Keywords

Cycloolivil 3064-05-9 Others oxidation-reduction Platelet aggregation Free radical scavengers Thrombin Isoolivil Platelets Aggregation Inhibitor Antioxidants inhibit inhibitor

 

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