Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering senescence in pancreatic and breast cancer cells through blocking the cell cycle in the G1 phase.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 1,980.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 2,289.00 |
Description | Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering senescence in pancreatic and breast cancer cells through blocking the cell cycle in the G1 phase. |
Source |
Molecular Weight | 354.402 |
Formula | C21H22O5 |
CAS No. | 74515-47-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Cristacarpin 74515-47-2 Apoptosis Cell Cycle/Checkpoint Immunology/Inflammation MAPK Microbiology/Virology p38 MAPK ROS CDK Antifection p53 inhibitor inhibit