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Benzthiazide

Benzthiazide
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Purity:99.79%
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Benzthiazide

Catalog No. T0782Cas No. 91-33-8
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
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Pack SizePriceAvailabilityQuantity
100 mg$39In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Product Introduction

Bioactivity
Description
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
AliasAquatag, Lemazide, Dihydrex
Chemical Properties
Molecular Weight431.94
FormulaC15H14ClN3O4S3
Cas No.91-33-8
Storage & Solubility Information
Storagestore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 45 mg/mL (104.19 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3151 mL11.5757 mL23.1514 mL115.7568 mL
5 mM0.4630 mL2.3151 mL4.6303 mL23.1514 mL
10 mM0.2315 mL1.1576 mL2.3151 mL11.5757 mL
20 mM0.1158 mL0.5788 mL1.1576 mL5.7878 mL
50 mM0.0463 mL0.2315 mL0.4630 mL2.3151 mL
100 mM0.0232 mL0.1158 mL0.2315 mL1.1576 mL

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