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AR-M 1000390 hydrochloride

Catalog No. T4236 CAS 209808-47-9

Synonyms: ARM390 Hydrochloride, ARM-390 HCl

AR-M 1000390 hydrochloride (ARM-390 HCl) , also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

AR-M 1000390 hydrochloride Chemical Structure

AR-M 1000390 hydrochloride, CAS 209808-47-9

Pack Size	Availability	Price/USD
5 mg	In stock	$ 64.00
10 mg	In stock	$ 106.00
25 mg	In stock	$ 219.00
50 mg	In stock	$ 396.00
100 mg	In stock	$ 595.00
1 mL * 10 mM (in DMSO)	In stock	$ 70.00

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Purity: 99.68%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AR-M 1000390 hydrochloride (ARM-390 HCl) , also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
Targets&IC50	δ opioid receptor:
In vitro	Does not trigger acute desensitization of the analgesic response
In vivo	Reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.

Synonyms	ARM390 Hydrochloride, ARM-390 HCl
Molecular Weight	384.94
Formula	C23H29ClN2O
CAS No.	209808-47-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 38.49 mg/mL (100 mM)

DMSO: 38.49 mg/mL (100 mM)

References and Literature

1. Marie N,etal.Pharmacological characterization of AR-M1000390 at human delta opioid receptors.Life Sci. 2003 Aug 15;73(13):1691-704. 2. Pradhan AA,etal.Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance.J Neurosci. 2010 Dec 8;30(49):16459-68.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Anti-Neurodegenerative Disease Compound Library Membrane Protein-targeted Compound Library Bioactive Compound Library Bioactive Compounds Library Max Neuronal Signaling Compound Library Neurotransmitter Receptor Compound Library Anti-Parkinson's Disease Compound Library Endocrinology-Hormone Compound Library Preclinical Compound Library

Related Products

Related compounds with same targets

MCOPPB triHydrochloride Mu opioid receptor antagonist 7 Ac-RYYRIK-NH2 acetate Difelikefalin acetate BRL 52537 hydrochloride SNC 80 ICI 199,441 hydrochloride Norbinaltorphimine dihydrochloride

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AR-M 1000390 hydrochloride 209808-47-9 Endocrinology/Hormones GPCR/G Protein Neuroscience Opioid Receptor AR-M1000390 Hydrochloride Inhibitor ARM 390 Hydrochloride ARM-390 Hydrochloride ARM390 Hydrochloride inhibit AR-M 1000390 AR-M 1000390 Hydrochloride ARM-390 HCl AR-M-1000390 Hydrochloride AR M 1000390 hydrochloride ARM 1000390 hydrochloride inhibitor

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