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AGX51

Catalog No. T10268 CAS 330834-54-3

AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.

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AGX51, CAS 330834-54-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 118.00
5 mg	In stock	$ 291.00
10 mg	In stock	$ 457.00
25 mg	In stock	$ 725.00
50 mg	In stock	$ 995.00
100 mg	In stock	$ 1,380.00
1 mL * 10 mM (in DMSO)	In stock	$ 319.00

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Purity: 99.85%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.
In vitro	AGX51 inhibits the Id1-E47 interaction. AGX51 is well-tolerated in mice and phenocopies the genetic loss of Id expression in AMD and ROP models by inhibiting retinal neovascularization. AGX51 may have utility in the management of multiple diseases[1].

Molecular Weight	431.52
Formula	C27H29NO4
CAS No.	330834-54-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

Ethanol: 95 mg/mL (220.15 mM), Need ultrasonic

DMSO: 95 mg/mL (220.15 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Wojnarowicz PM, et al. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep. 2019 Oct 1;29(1):62-75.e7.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AGX51 330834-54-3 Others ubiquitin AGX 51 Inhibitor anti-tumor TNBC AGX-51 inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.