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AGX51

AGX51
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Purity:99.85%
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AGX51

Catalog No. T10268Cas No. 330834-54-3
AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.
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Pack SizePriceAvailabilityQuantity
1 mg$118In Stock
5 mg$291In Stock
10 mg$457In Stock
25 mg$725In Stock
50 mg$995In Stock
100 mg$1,380In Stock
1 mL x 10 mM (in DMSO)$319In Stock
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Product Introduction

Bioactivity
Description
AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.
In vitro
AGX51 inhibits the Id1-E47 interaction. AGX51 is well-tolerated in mice and phenocopies the genetic loss of Id expression in AMD and ROP models by inhibiting retinal neovascularization. AGX51 may have utility in the management of multiple diseases[1].
Chemical Properties
Molecular Weight431.52
FormulaC27H29NO4
Cas No.330834-54-3
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 95 mg/mL (220.15 mM)
DMSO: 95 mg/mL (220.15 mM)
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM2.3174 mL11.5869 mL23.1739 mL115.8695 mL
5 mM0.4635 mL2.3174 mL4.6348 mL23.1739 mL
10 mM0.2317 mL1.1587 mL2.3174 mL11.5869 mL
20 mM0.1159 mL0.5793 mL1.1587 mL5.7935 mL
50 mM0.0463 mL0.2317 mL0.4635 mL2.3174 mL
100 mM0.0232 mL0.1159 mL0.2317 mL1.1587 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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