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3-Methoxyflavone

Name: 3-Methoxyflavone
Brand: TargetMol
SKU: T7994
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7994Cas No. 7245-02-5

3-Methoxyflavone is a Flavonoids, with antiviral activity

3-Methoxyflavone

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Purity: 99.97%

Catalog No. T7994Cas No. 7245-02-5

3-Methoxyflavone is a Flavonoids, with antiviral activity

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$30	In Stock	In Stock
500 mg	$61	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White to Yellow

Resource Download

COA LCMS HNMR

Product Introduction

3-Methoxyflavone AI Summary

3-Methoxyflavone exhibits a gastric protective effect in rats, providing 41.0% protection from gastric damage compared to the control group after intraperitoneal administration of 20 mg/Kg. The compound is a bioactive inhibitor of human BCRP (Breast Cancer Resistance Protein), inhibiting the efflux function with IC50 values of 1280.0 nM and 1210.0 nM in MDCK2 cell assays measuring the accumulation of substrates pheophorbide-A and Hoechst 33342, respectively, after a 30-minute preincubation period and subsequent 120-minute measurement using flow cytometry and fluorescence assay. Additionally, 3-Methoxyflavone exhibits no significant inhibition of human TNKS1 (1030 to 1317) activity with an IC50 greater than 10000.0 nM in assays using NAD+ as a substrate..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

3-Methoxyflavone is a Flavonoids, with antiviral activity

Chemical Properties

Molecular Weight	252.26
Formula	C₁₆H₁₂O₃
Cas No.	7245-02-5
Smiles	COc1c(oc2ccccc2c1=O)-c1ccccc1
Relative Density.	1.26g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (109.01 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.93 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9642 mL	19.8208 mL	39.6416 mL	198.2082 mL
5 mM	0.7928 mL	3.9642 mL	7.9283 mL	39.6416 mL
10 mM	0.3964 mL	1.9821 mL	3.9642 mL	19.8208 mL
20 mM	0.1982 mL	0.9910 mL	1.9821 mL	9.9104 mL
50 mM	0.0793 mL	0.3964 mL	0.7928 mL	3.9642 mL
100 mM	0.0396 mL	0.1982 mL	0.3964 mL	1.9821 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc