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2-TEDC

Catalog No. T22502 CAS 132465-10-2

2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.2-TEDC can be used in the study of atherosclerosis.

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2-TEDC, CAS 132465-10-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 34.00
5 mg	In stock	$ 80.00
10 mg	In stock	$ 139.00
25 mg	In stock	$ 289.00
50 mg	In stock	$ 455.00
100 mg	In stock	$ 788.00
500 mg	In stock	$ 1,590.00
1 mL * 10 mM (in DMSO)	In stock	$ 89.00

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Purity: 99.75%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.2-TEDC can be used in the study of atherosclerosis.
Targets&IC50	12-LOX:0.013 μM, 15-LOX:0.5 μM, 5-LOX:0.09 μM
In vitro	2-TEDC exhibits potent inhibition against 5-, 12-, and 15-lipoxygenase, with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.[1]

Molecular Weight	315.34
Formula	C16H13NO4S
CAS No.	132465-10-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90.0 mg/mL (285.4 mM), Sonication is recommended.

Ethanol: 25 mM

References and Literature

1. Cho H, et al. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem. 1991;34(4):1503-1505. 2. Ni N, et al. Singapore Grouper Iridovirus Disturbed Glycerophospholipids Homeostasis: Cytosolic Phospholipase A2 Was Essential for Virus Replication. Int J Mol Sci. 2021;22(22):12597.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library

Related Products

Related compounds with same targets

5-LOX-IN-2 RWJ 63556 Licofelone Silychristin Trichosanatine 4-Methyldaphnetin 1-Naphthyl 3,5-dinitrobenzoate COX-2/15-LOX-IN-4

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

2-TEDC 132465-10-2 Metabolism Lipoxygenase 2TEDC 2 TEDC inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.