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2-Chloro-1-(4-fluorobenzyl)benzimidazole

🥰Excellent
Catalog No. T7478Cas No. 84946-20-3

2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).

2-Chloro-1-(4-fluorobenzyl)benzimidazole

2-Chloro-1-(4-fluorobenzyl)benzimidazole

🥰Excellent
Purity: 99.64%
Catalog No. T7478Cas No. 84946-20-3
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
Pack SizePriceAvailabilityQuantity
1 g$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.64%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
Chemical Properties
Molecular Weight260.69
FormulaC14H10ClFN2
Cas No.84946-20-3
SmilesC(N1C=2C(N=C1Cl)=CC=CC2)C3=CC=C(F)C=C3
Relative Density.1.3 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (210.98 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8360 mL19.1799 mL38.3597 mL191.7987 mL
5 mM0.7672 mL3.8360 mL7.6719 mL38.3597 mL
10 mM0.3836 mL1.9180 mL3.8360 mL19.1799 mL
20 mM0.1918 mL0.9590 mL1.9180 mL9.5899 mL
50 mM0.0767 mL0.3836 mL0.7672 mL3.8360 mL
100 mM0.0384 mL0.1918 mL0.3836 mL1.9180 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

aldose reductase2-Chloro-1-(4-fluorobenzyl)benzimidazole2Chloro1(4fluorobenzyl)benzimidazole2 Chloro 1 (4 fluorobenzyl)benzimidazole
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