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EM-12

🥰Excellent
Catalog No. T41362Cas No. 26581-81-7
Alias Phthalimidinoglutarimide, 2-(2,6-Dioxopiperidin-3-yl)phthalimidine

2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active and significantly more stable against hydrolysis than Thalidomide, enhancing 1,2-dimethylhydrazine-induced rat colon adenocarcinomas [1] [2].

EM-12

EM-12

🥰Excellent
Purity: 99.34%
Catalog No. T41362Alias Phthalimidinoglutarimide, 2-(2,6-Dioxopiperidin-3-yl)phthalimidineCas No. 26581-81-7
2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active and significantly more stable against hydrolysis than Thalidomide, enhancing 1,2-dimethylhydrazine-induced rat colon adenocarcinomas [1] [2].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$40In StockIn Stock
25 mg$81In StockIn Stock
50 mg$118In StockIn Stock
100 mg$179In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.34%
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Product Introduction

Bioactivity
Description
2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active and significantly more stable against hydrolysis than Thalidomide, enhancing 1,2-dimethylhydrazine-induced rat colon adenocarcinomas [1] [2].
SynonymsPhthalimidinoglutarimide, 2-(2,6-Dioxopiperidin-3-yl)phthalimidine
Chemical Properties
Molecular Weight244.25
FormulaC13H12N2O3
Cas No.26581-81-7
SmilesO=C1N(CC=2C1=CC=CC2)C3C(=O)NC(=O)CC3
Relative Density.1.2650 g/cm3 (Estimated)
ColorBlue
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 11 mg/mL (45.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0942 mL20.4708 mL40.9417 mL204.7083 mL
5 mM0.8188 mL4.0942 mL8.1883 mL40.9417 mL
10 mM0.4094 mL2.0471 mL4.0942 mL20.4708 mL
20 mM0.2047 mL1.0235 mL2.0471 mL10.2354 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

EM-12EM12EM 12
Related Tags: buy EM-12 | purchase EM-12 | EM-12 cost | order EM-12 | EM-12 chemical structure | EM-12 formula | EM-12 molecular weight
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