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Pseudolaric acid B β-D-glucoside

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Catalog No. T5741Cas No. 98891-41-9
Alias Pseudolaric acid B-glucopyranoside

Pseudolaric acid B β-D-glucoside (Pseudolaric acid B-glucopyranoside) is a natural product derived from Pseudolarix amabilis.

Pseudolaric acid B β-D-glucoside

Pseudolaric acid B β-D-glucoside

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Purity: 98.55%
Catalog No. T5741Alias Pseudolaric acid B-glucopyranosideCas No. 98891-41-9
Pseudolaric acid B β-D-glucoside (Pseudolaric acid B-glucopyranoside) is a natural product derived from Pseudolarix amabilis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$40In StockIn Stock
10 mg$64In StockIn Stock
25 mg$106In StockIn Stock
50 mg$155In StockIn Stock
1 mL x 10 mM (in DMSO)$52In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.55%
Appearance:Solid
Color:White
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Product Introduction

Pseudolaric acid B β-D-glucoside AI Summary
Pseudolaric acid B β-D-glucoside exhibits both antimicrobial and antifungal activities, particularly against Candida albicans. Through an agar-well diffusion assay at a concentration of 1 mg/mL, it demonstrated antimicrobial activity with an inhibition zone of less than 1.0 mm. In mouse models infected with Candida albicans NIH B311, the compound was administered at dosages of 7 mg/kg, 3 mg/kg, and 3.5 mg/kg at specific intervals post-infection. This treatment resulted in significant reductions in the number of colony-forming units recovered per mg of kidney tissue, with antifungal activity ranging from 9.91% to 46.59% relative to the control group. These findings highlight Pseudolaric acid B β-D-glucoside's potential in reducing fungal burden in infected tissues..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Pseudolaric acid B β-D-glucoside (Pseudolaric acid B-glucopyranoside) is a natural product derived from Pseudolarix amabilis.
SynonymsPseudolaric acid B-glucopyranoside
Chemical Properties
Molecular Weight594.60
FormulaC29H38O13
Cas No.98891-41-9
Smiles[H][C@@]12CC[C@]3(CC=C(CC[C@]13OC(C)=O)C(=O)OC)C(=O)O[C@]2(C)\C=C\C=C(/C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.1.42 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50.00 mg/mL (84.09 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.00 mg/mL (3.36 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6818 mL8.4090 mL16.8180 mL84.0901 mL
5 mM0.3364 mL1.6818 mL3.3636 mL16.8180 mL
10 mM0.1682 mL0.8409 mL1.6818 mL8.4090 mL
20 mM0.0841 mL0.4205 mL0.8409 mL4.2045 mL
50 mM0.0336 mL0.1682 mL0.3364 mL1.6818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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