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Boc-Lys(Ac)-AMC

Name: Boc-Lys(Ac)-AMC
Brand: TargetMol
SKU: T36578
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36578Cas No. 233691-67-3

Alias Boc-L-Lys(Ac)-AMC

Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).

Boc-Lys(Ac)-AMC

🥰Excellent

Purity: 99.87%

Catalog No. T36578Alias Boc-L-Lys(Ac)-AMCCas No. 233691-67-3

Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$42	-	In Stock
10 mg	$68	-	In Stock
25 mg	$128	-	In Stock
50 mg	$187	-	In Stock
100 mg	$275	-	In Stock
200 mg	$397	-	In Stock
1 mL x 10 mM (in DMSO)	$46	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

Batch Information

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Purity:99.87%

Resource Download

COA HNMR HPLC MS

Product Introduction

Bioactivity

Description	Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).
In vitro	HDACs act by catalyzing the deacetylation reaction of the substrate Boc-Lys(Ac)-AMC. Upon addition of trypsin-containing development reagents, the deacetylation products are converted into quantifiable fluorescent markers that can be used both in screening methods and to help identify potential HDAC inhibitors. [1]
Synonyms	Boc-L-Lys(Ac)-AMC

Chemical Properties

Molecular Weight	445.51
Formula	C₂₃H₃₁N₃O₆
Cas No.	233691-67-3
Smiles	CC=1C=2C(=CC(NC([C@@H](NC(OC(C)(C)C)=O)CCCCNC(C)=O)=O)=CC2)OC(=O)C1
Relative Density.	1.209 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (179.57 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2446 mL	11.2231 mL	22.4462 mL	112.2309 mL
5 mM	0.4489 mL	2.2446 mL	4.4892 mL	22.4462 mL
10 mM	0.2245 mL	1.1223 mL	2.2446 mL	11.2231 mL
20 mM	0.1122 mL	0.5612 mL	1.1223 mL	5.6115 mL
50 mM	0.0449 mL	0.2245 mL	0.4489 mL	2.2446 mL
100 mM	0.0224 mL	0.1122 mL	0.2245 mL	1.1223 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc