Powder: -20°C for 3 years | In solvent: -80°C for 1 year
YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor that inhibits SIK1, SIK2 and SIK3 with IC50s of 2.12 nM, 1.40 nM and 2.86 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 93.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 629.00 | |
50 mg | In stock | $ 896.00 | |
100 mg | In stock | $ 1,220.00 | |
500 mg | In stock | $ 2,450.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 253.00 |
Description | YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor that inhibits SIK1, SIK2 and SIK3 with IC50s of 2.12 nM, 1.40 nM and 2.86 nM. |
Targets&IC50 | SIK3:2.86 nM, SIK1:2.12 nM, SIK2:1.40 nM |
In vitro | In a dose-dependent manner, YKL 06-062 (0.0004-16 μM; 3 h) enhances MITF mRNA expression.[1] |
Molecular Weight | 525.69 |
Formula | C31H39N7O |
CAS No. | 2172617-16-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (42.8 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
YKL-06-062 2172617-16-0 PI3K/Akt/mTOR signaling SIK YKL06062 YKL 06 062 inhibitor inhibit