Home Tools
Log in
Cart

Triptorelin acetate(57773-63-4 free base)

Catalog No. T21410   CAS 140194-24-7
Synonyms: Wy 42422, Triptorelin Acetate, CL 118532, AY 25650, CL 118,532, Wy 42462, BIM 21003

Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by causing constant stimulation of the pituitary. Triptorelin acetate(57773-63-4 free base) may be used in the treatment of hormone-responsive cancers such as breast cancer or prostate cancer, precocious puberty, estrogen-dependent conditions, and assisted reproduction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Triptorelin acetate(57773-63-4 free base) Chemical Structure
Triptorelin acetate(57773-63-4 free base), CAS 140194-24-7
Pack Size Availability Price/USD Quantity
5 mg In stock $ 50.00
10 mg In stock $ 75.00
25 mg In stock $ 128.00
50 mg In stock $ 192.00
100 mg In stock $ 287.00
200 mg In stock $ 431.00
1 mL * 10 mM (in DMSO) In stock $ 125.00
Bulk Inquiry
Get quote
Select Batch  
Purity: 99.90%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by causing constant stimulation of the pituitary. Triptorelin acetate(57773-63-4 free base) may be used in the treatment of hormone-responsive cancers such as breast cancer or prostate cancer, precocious puberty, estrogen-dependent conditions, and assisted reproduction.
Synonyms Wy 42422, Triptorelin Acetate, CL 118532, AY 25650, CL 118,532, Wy 42462, BIM 21003
Molecular Weight 1371.53
Formula C66H86N18O15
CAS No. 140194-24-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: 65 mg/ml (47.39 mM)

TargetMolReferences and Literature

1. Klein K, Yang J, Aisenberg J,et al. Efficacy and safety of triptorelin 6-month formulation in patients with central precocious puberty. J Pediatr Endocrinol Metab. 2016 Feb 17. pii: /j/jpem.ahead-of-print/jpem-2015-0376/jpem-2015-0376.xml. doi: 10.1515/jpem-2015-0376. [Epub ahead of print] PubMed PMID: 26887034. 2. Meattini I, Saieva C, et al. Impact of age on cytotoxic-induced ovarian failure in breast cancer treated with adjuvant chemotherapy and triptorelin. Future Oncol. 2016 Mar;12(5):625-35. doi: 10.2217/fon.15.357. Epub 2016 Feb 3. PubMed PMID: 26837239. 3. Bellet M, Gray KP, Francis PA,et al. Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy. J Clin Oncol. 2016 Jan 4. pii: JCO612259. [Epub ahead of print] PubMed PMID: 26729437. 4. Lambertini M, Boni L, Michelotti A,et al. Ovarian Suppression With Triptorelin During Adjuvant Breast Cancer Chemotherapy and Long-term Ovarian Function, Pregnancies, and Disease-Free Survival: A Randomized Clinical Trial. JAMA. 2015 Dec 22-29;314(24):2632-40. doi: 10.1001/jama.2015.17291. PubMed PMID: 26720025.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Peptide Compound Library Anti-Cancer Active Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Drug Repurposing Compound Library Anti-Prostate Cancer Compound Library GPCR Compound Library Preclinical Compound Library Anti-Infection Compound Library

Related Products

Related compounds with same targets
AG 045572 LHRH Goserelin acetate Cetrorelix diacetate Alarelin Acetate Nafarelin acetate(76932-56-4 free base) Histrelin acetate Relugolix

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Triptorelin acetate(57773-63-4 free base) 140194-24-7 GPCR/G Protein GNRH Receptor BIM21003 Triptorelin acetate(57773634 free base) Wy 42422 Triptorelin Acetate BIM-21003 CL-118532 CL 118532 AY 25650 CL 118,532 Triptorelin acetate(57773 63 4 free base) AY-25650 Wy 42462 CL118532 AY25650 BIM 21003 inhibitor inhibit

 

TargetMol