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Tedizolid Phosphate

Catalog No. T6998   CAS 856867-55-5
Synonyms: TR-701FA, Torezolid phosphate

Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.

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Tedizolid Phosphate Chemical Structure
Tedizolid Phosphate, CAS 856867-55-5
Pack Size Availability Price/USD Quantity
2 mg In stock $ 41.00
5 mg In stock $ 67.00
10 mg In stock $ 97.00
25 mg In stock $ 115.00
50 mg In stock $ 147.00
100 mg In stock $ 197.00
500 mg In stock $ 489.00
1 mL * 10 mM (in DMSO) In stock $ 68.00
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Purity: 99.84%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
In vitro Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next-generation oxazolidinone, with high potency against Gram-positive species, including methicillin-resistant Staphylococcus aureus (MRSA)[2]. Tedizolid is 4-fold more potent than linezolid against PRSP isolates in vitro[1].
In vivo Tedizolid has excellent penetration into pulmonary epithelial lining fluid (ELF). Tedizolid phosphate administered to mice orally or intravenously is effective in vivo against systemic infection with PRSP isolates. Oral tedizolid phosphate is also effective in vivo against pneumonia induced with a PSSP strain[1].
Synonyms TR-701FA, Torezolid phosphate
Molecular Weight 450.32
Formula C17H16FN6O6P
CAS No. 856867-55-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 21 mg/mL (46.6 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

TargetMolReferences and Literature

1. Choi S, et al. Antimicrob Agents Chemother. 2012, 56(9):4713-7. 2. Prokocimer P, et al. Antimicrob Agents Chemother. 2012, 56(9):4608-13.

Related compound libraries

This product is contained In the following compound libraries:
Immunology/Inflammation Compound Library Bioactive Compounds Library Max Bioactive Compound Library FDA-Approved & Pharmacopeia Drug Library Pediatric Drug Library Orally Active Compound Library Human Metabolite Library Anti-Infection Compound Library Clinical Compound Library Antibiotics Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tedizolid Phosphate 856867-55-5 Microbiology/Virology Antibacterial Antibiotic TR-701FA inhibit Tedizolid Torezolid Phosphate Torezolid phosphate Bacterial Inhibitor inhibitor

 

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