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TSHR antagonist S37

Catalog No. T13216 CAS 1217616-61-9

TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).

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TSHR antagonist S37, CAS 1217616-61-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
In vitro	cAMP activation induced by the small molecule agonist C2 reduced by TSHR antagonist S37.

Molecular Weight	460.57
Formula	C25H20N2O3S2
CAS No.	1217616-61-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 65 mg/ml (141.13 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Marcinkowski P, et al. A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy. Thyroid. 2019 Jan;29(1):111-123.

Related Products

Related compounds with same targets

D3-βArr TSHR antagonist S37 NCGC00229600 ML-109

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Keywords

TSHR antagonist S37 1217616-61-9 G蛋白偶联受体 TSH Receptor TSHR antagonist S-37 Inhibitor inhibitor inhibit

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