Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sucralfate (Sucrose octasulfate–aluminum complex) is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 43.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | Sucralfate (Sucrose octasulfate–aluminum complex) is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers. |
In vitro | Sucralfate may inhibit intestinal epithelial motility by sterically interfering with adhesion to collagen I[3]. It protects RGMl cells from acid- and pepsin-induced damage[4]. |
In vivo | The protective effects of sucralfate against ARC(acute radiation colitis) may be partially due to the supression of radiation-induced apoptosis by way of p53 in the colon and the protection of the colonic epithelial stem cell region[2]. |
Cell Research | Sucralfate is dissolved or suspended in culture medium containing 20% FBS. Cells are incubated with the agent at 37°C under 5% CO2, in air for 0.5-4 h. In some cases, cells are treated with 10-5mol/L indomethacin for 4h before the addition of the agent to determine whether or not intracellular prostaglandins are involved in the protective mechanisms of sucralfate. (Only for Reference) |
Synonyms | Sucrose octasulfate–aluminum complex |
Molecular Weight | 2086.75 |
Formula | C12H54Al16O75S8 |
CAS No. | 54182-58-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20.87 mg/ml (10 mM)
H2O: 0.4 mg/mL (0.20 mM), ultrasonic and adjust pH to 2 with HCl
You can also refer to dose conversion for different animals. More
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Sucralfate 54182-58-0 Angiogenesis GPCR/G Protein Immunology/Inflammation Microbiology/Virology Others Tyrosine Kinase/Adaptors FGFR Antibacterial Prostaglandin Receptor Bacterial Inhibitor inhibit Sucrose octasulfate-aluminum complex Sucrose octasulfate–aluminum complex inhibitor