Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 589.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM). |
Targets&IC50 | GAK:3.1 nM (Ki) |
In vitro | SGC-GAK-1 potently binds GAK (Ki: 3.1 nM; Kd: 1.9 nM). SGC-GAK-1 showed strong growth inhibition in LNCaP, VCaP, and 22Rv1 cells at 10 μM, but the minimal effect in PC3 and DU145 cells. In dose-response SGC-GAK-1 showed potent antiproliferative activity in LNCaP and 22Rv1 cells at a similar dose range that it engages GAK. |
Molecular Weight | 389.24 |
Formula | C18H17BrN2O3 |
CAS No. | 2226517-76-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 15 mg/mL
DMSO: 55 mg/mL (141.3 mM)
You can also refer to dose conversion for different animals. More
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SGC-GAK-1 2226517-76-4 Cell Cycle/Checkpoint Metabolism Serine/threonin kinase SGCGAK1 Inhibitor SGC GAK 1 inhibit inhibitor