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S-Methoprene

Catalog No. T19752   CAS 65733-16-6
Synonyms: ZR-2458, ZR-2458, ZR2458, ZR 2458, (+)-Methoprene, Preco,

S-Methoprene is a juvenile insect growth hormone analog. It alters Ca 2+ signaling and redox activity of cytochrome oxidase and induces male sex differentiation.

S-Methoprene, CAS 65733-16-6
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Biological Description
Chemical Properties
Storage & Solubility Information
Description S-Methoprene is a juvenile insect growth hormone analog. It alters Ca 2+ signaling and redox activity of cytochrome oxidase and induces male sex differentiation.
Synonyms ZR-2458 , ZR-2458 , ZR2458 , ZR 2458 , (+)-Methoprene , Preco ,
Purity
Molecular Weight 310.47
Formula C19H34O3
CAS No. 65733-16-6

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Dhopeshwarkar AS, Nicholson RA. Benzophenanthridine alkaloid, piperonyl butoxide and (S)-methoprene action at the cannabinoid-1 receptor (CB1-receptor) pathway of mouse brain: Interference with [(3)H]CP55940 and [(3)H]SR141716A binding and modification of WIN55212-2-dependent inhibition of synaptosomal l-glutamate release. Eur J Pharmacol. 2014 Jan 15;723:431-41. doi: 10.1016/j.ejphar.2013.10.059. Epub 2013 Nov 8. PubMed PMID: 24211785. 2. Dryden MW, Smith V, Davis WL, Settje T, Hostetler J. Evaluation and comparison of a flumethrin-imidacloprid collar and repeated monthly treatments of fipronil/(s)-methoprene to control flea, Ctenocephalides f. felis, infestations on cats for eight months. Parasit Vectors. 2016 May 17;9(1):287. doi: 10.1186/s13071-016-1575-5. PubMed PMID: 27189592; PubMed Central PMCID: PMC4869298. 3. Knaus M, Abu-Madi MA, Ibarra-Velarde F, Kok DJ, Kusi I, Postoli R, Chester ST, Rosentel J, Alva R, Irwin J, Visser M, Winter R, Rehbein S. Efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination against naturally acquired intestinal nematode and cestode infections in cats. Vet Parasitol. 2014 Apr 28;202(1-2):18-25. doi: 10.1016/j.vetpar.2014.02.033. PubMed PMID: 24703071. 4. Rehbein S, Capári B, Duscher G, Keidane D, Kirkova Z, Petkevičius S, Rapti D, Wagner A, Wagner T, Chester ST, Rosentel J, Tielemans E, Visser M, Winter R, Kley K, Knaus M. Efficacy against nematode and cestode infections and safety of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination product in domestic cats under field conditions in Europe. Vet Parasitol. 2014 Apr 28;202(1-2):10-7. doi: 10.1016/j.vetpar.2014.02.032. PubMed PMID: 24703070.

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