Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mechanism of UVA breaking DNA structure.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 117.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 458.00 | |
25 mg | In stock | $ 823.00 | |
50 mg | In stock | $ 1,090.00 |
Description | Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mechanism of UVA breaking DNA structure. |
In vitro | Pterin-6-carboxylic acid induces DNA photooxidation specifically at consecutive G residues through electron transfer[1]. Pterin-6-carboxylic acid bind to the active site of phosphodiesterase 5 with the binding energy value of -7.1 and 2.05A° 2.23A° when compared with other compound found in the plant. In silico studies hypothesized that pterin-6-carboxylic acid can be an inhibitory agent for PDE5 protein which could be a potential drug candidate for the treatment of erectile dysfunction[2]. |
Synonyms | 6-Carboxypterin |
Molecular Weight | 207.15 |
Formula | C7H5N5O3 |
CAS No. | 948-60-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
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Pterine-6-carboxylic acid 948-60-7 DNA Damage/DNA Repair Metabolism DNA PDE 6-Carboxypterin inhibitor inhibit