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PDEC-NB

Name: PDEC-NB
Brand: TargetMol
SKU: T18529
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18529Cas No. 874302-76-8

Alias 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate

PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) is a disulfide cleavable linker. PDEC-NB can be used for the antibody-drug conjugate (ADC).

PDEC-NB

🥰Excellent

Purity: 99.26%

Catalog No. T18529Alias 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl CarbonateCas No. 874302-76-8

PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) is a disulfide cleavable linker. PDEC-NB can be used for the antibody-drug conjugate (ADC).

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
50 mg	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Questions

Batch Information

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Purity:99.26%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) is a disulfide cleavable linker. PDEC-NB can be used for the antibody-drug conjugate (ADC).
Synonyms	4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate

Chemical Properties

Molecular Weight	352.39
Formula	C₁₄H₁₂N₂O₅S₂
Cas No.	874302-76-8
Smiles	[O-][N+](=O)c1ccc(OC(=O)OCCSSc2ccccn2)cc1
Relative Density.	1.46 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 88 mg/mL (249.72 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8378 mL	14.1888 mL	28.3776 mL	141.8882 mL
5 mM	0.5676 mL	2.8378 mL	5.6755 mL	28.3776 mL
10 mM	0.2838 mL	1.4189 mL	2.8378 mL	14.1888 mL
20 mM	0.1419 mL	0.7094 mL	1.4189 mL	7.0944 mL
50 mM	0.0568 mL	0.2838 mL	0.5676 mL	2.8378 mL
100 mM	0.0284 mL	0.1419 mL	0.2838 mL	1.4189 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc