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Oxacillin

Catalog No. T61951 CAS 66-79-5

Oxacillin is an orally active synthetic penicillin. Oxacillin shows good bactericidal activity against staphylococci and other gram-positive pathogens.

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Oxacillin, CAS 66-79-5

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Oxacillin is an orally active synthetic penicillin. Oxacillin shows good bactericidal activity against staphylococci and other gram-positive pathogens.
In vitro	Oxacillin effectively inhibits Gram-positive pathogens, exhibiting minimum inhibitory concentrations (MICs) of 0.05, 0.09, 0.32, and 0.80 μg/mL against Group A streptococci, Pneumococci, susceptible staphylococci, and penicillin-resistant staphylococci, respectively [1]. Additionally, strains resistant to Oxacillin show a high level of resistance to other penicillins [1].
In vivo	Oxacillin, administered subcutaneously at dosages ranging from 50 to 800 mg/kg (single dose), demonstrated a curative dose (CD 50) of 253.3 mg/kg for CD-1 strain male albino mice infected with Staphylococcus aureus Evans. In contrast, the oral CD 50 for Oxacillin was found to be 187.2 mg/kg. This therapeutic activity highlights Oxacillin's effectiveness against S. aureus Evans infections in mice [2].

Molecular Weight	401.44
Formula	C19H19N3O5S
CAS No.	66-79-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Dose Conversion

You can also refer to dose conversion for different animals. More

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Oxacillin 66-79-5 inhibitor inhibit

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