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Limonin glucoside

Catalog No. T27834   CAS 123564-61-4
Synonyms: CCRIS-6986, CCRIS 6986, CCRIS6986

Limonin glucoside is a natural product in citrus fruits. It inhibits expression of HIV-1 and HTLV-1 in infected cells, induces apoptosis in colon adenocarcinoma cells, and exhibits larvicidal activity against species of Aedes.

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Limonin glucoside Chemical Structure
Limonin glucoside, CAS 123564-61-4
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Limonin glucoside is a natural product in citrus fruits. It inhibits expression of HIV-1 and HTLV-1 in infected cells, induces apoptosis in colon adenocarcinoma cells, and exhibits larvicidal activity against species of Aedes.
Synonyms CCRIS-6986, CCRIS 6986, CCRIS6986
Molecular Weight 650.674
Formula C32H42O14
CAS No. 123564-61-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Chidambara Murthy KN, Jayaprakasha GK, Kumar V, Rathore KS, Patil BS. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem. 2011 Mar 23;59(6):2314-23. doi: 10.1021/jf104498p. Epub 2011 Feb 21. PubMed PMID: 21338095. 2. Somasundaram S, Price J, Pearce K, Shuck R, Jayaprakasha GK, Patil B. Citrus limonin lacks the antichemotherapeutic effect in human models of breast cancer. J Nutrigenet Nutrigenomics. 2012;5(2):106-14. Epub 2012 Aug 17. PubMed PMID: 22907263. 3. Breksa AP 3rd, Manners GD. Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside. J Agric Food Chem. 2006 May 31;54(11):3827-31. PubMed PMID: 16719503. 4. Zunino SJ, Storms DH, Freytag TL, Adkins YC, Bonnel EL, Woodhouse LR, Breksa AP 3rd, Manners GD, Mackey BE, Kelley DS. Dietary supplementation with purified citrus limonin glucoside does not alter ex vivo functions of circulating T lymphocytes or monocytes in overweight/obese human adults. Nutr Res. 2016 Jan;36(1):24-30. doi: 10.1016/j.nutres.2015.10.011. Epub 2015 Oct 31. PubMed PMID: 26773778.

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Keywords

Limonin glucoside 123564-61-4 CCRIS-6986 CCRIS 6986 CCRIS6986 inhibitor inhibit

 

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