Powder: -20°C for 3 years
In solvent: -80°C for 2 years
KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
Description | KPT-185 is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest. |
Targets&IC50 | CRM1:100-500nM |
Cell Research | Cells are seeded into 96-well plates and treated for 24, 48, and 72 hours with KPT-SINE at various concentrations ranging from 10 nM to 10 μM. Cell viability is evaluated using the cell proliferation reagent WST-1 according to the manufacturer's protocol. The absorbance of wells at 450 nm (reference wavelength, 650 nm) is measured with a microplate reader. (Only for Reference) |
Synonyms | KPT-185, KPT 185 |
Molecular Weight | 355.317 |
Formula | C16H16F3N3O3 |
CAS No. | 1333151-73-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: <1 mg/mL
DMSO: 66 mg/mL (185.8 mM)
Ethanol: 66 mg/mL (185.8 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KPT185 1333151-73-7 离子通道 CRM1 KPT 185 KPT-185 Inhibitor inhibitor inhibit