Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 150.00 | |
10 mg | In stock | $ 231.00 | |
25 mg | In stock | $ 427.00 | |
50 mg | In stock | $ 632.00 | |
100 mg | In stock | $ 882.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 125.00 |
Description | GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively. |
Targets&IC50 | monkey RIP1:20 nM, human RIP1:16 nM |
In vitro | GSK2982772 ?potently binds to RIP1 with exquisite kinase specificity and has excellent activity in blocking many TNF-dependent cellular responses.?Highlighting its potential as a novel anti-inflammatory agent, the inhibitor was also able to reduce spontaneous production of cytokines from human ulcerative colitis explants. |
Molecular Weight | 377.4 |
Formula | C20H19N5O3 |
CAS No. | 1622848-92-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (264.97 mM)
You can also refer to dose conversion for different animals. More
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GSK2982772 1622848-92-3 Apoptosis NF-Κb RIP kinase inhibit Receptor-interacting protein kinases RIPK Inhibitor GSK-2982772 GSK 2982772 inhibitor