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Estramustine phosphate

Catalog No. T4451L CAS 4891-15-0

Synonyms: LS 299, NSC 89199, NSC-89199, LS-299, LS299

Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.

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Estramustine phosphate Chemical Structure

Estramustine phosphate, CAS 4891-15-0

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.

Synonyms	LS 299, NSC 89199, NSC-89199, LS-299, LS299
Molecular Weight	520.38
Formula	C23H32Cl2NO6P
CAS No.	4891-15-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Petrioli R, Roviello G, Fiaschi AI, Laera L, Bianco V, Ponchietti R, Barbanti G, Francini E. Low-Dose Estramustine Phosphate and Concomitant Low-Dose Acetylsalicylic Acid in Heavily Pretreated Patients With Advanced Castration-Resistant Prostate Cancer. Clin Genitourin Cancer. 2015 Oct;13(5):441-6. doi: 10.1016/j.clgc.2015.03.004. Epub 2015 Mar 26. PubMed PMID: 25920994. 2. Aurilio G, Graffeo R, Bagnardi V, Nolè F, Adamoli L, Pagani O, Gallerani E, Ferrari B, Pruneri G, Goldhirsch A. Estramustine phosphate sodium in heavily pretreated patients with metastatic breast cancer: a retrospective consecutive case series. Int J Clin Oncol. 2015 Feb;20(1):90-4. doi: 10.1007/s10147-014-0694-2. Epub 2014 Apr 12. PubMed PMID: 24722887. 3. Matsumoto K, Tanaka N, Hayakawa N, Ezaki T, Suzuki K, Maeda T, Ninomiya A, Nakamura S. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. doi: 10.1007/s12032-013-0717-2. Epub 2013 Sep 5. PubMed PMID: 24005812. 4. Hayakawa N, Matsumoto K, Sato A, Sakamoto H, Ezaki T, Maeda T, Ninomiya A, Nakamura S. Efficacy of tegafur-uracil (UFT) administration in castration-resistant prostate cancer patients with a history of both alternative antiandrogen therapy and estramustine phosphate sodium hydrate therapy. Int Urol Nephrol. 2014 Jun;46(6):1123-9. doi: 10.1007/s11255-013-0634-5. Epub 2013 Dec 20. PubMed PMID: 24356920.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Estramustine phosphate 4891-15-0 LS 299 NSC 89199 Estramustine Phosphate NSC-89199 NSC89199 LS-299 LS299 inhibitor inhibit

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