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Delafloxacin

Catalog No. T4063 CAS 189279-58-1

Synonyms: ABT492, WQ-3034, RX-3341

Delafloxacin (WQ-3034) (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. It has potent inhibitory against levofloxacin-resistant Streptococcus pneumoniae strains (MIC: 0.0078-0.125 μg/ml).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Delafloxacin, CAS 189279-58-1

Pack Size	Availability	Price/USD
10 mg	In stock	$ 39.00
25 mg	In stock	$ 80.00
50 mg	In stock	$ 153.00
100 mg	In stock	$ 243.00
200 mg	In stock	$ 361.00
500 mg	In stock	$ 588.00
1 mL * 10 mM (in DMSO)	In stock	$ 35.00

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Purity: 99.81%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Delafloxacin (WQ-3034) (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent. It has potent inhibitory against levofloxacin-resistant Streptococcus pneumoniae strains (MIC: 0.0078-0.125 μg/ml).

Synonyms	ABT492, WQ-3034, RX-3341
Molecular Weight	440.76
Formula	C18H12ClF3N4O4
CAS No.	189279-58-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (56.72 mM)

References and Literature

1. Gunderson SM, Hayes RA, Quinn JP, In vitro pharmacodynamic activities of ABT-492, a novel quinolone, compared to those of levofloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob Agents Chemother. 2004 Jan;48(1):203-8. 2. Goldstein EJ, Citron DM, Merriam CV, In vitro activities of ABT-492, a new fluoroquinolone, against 155 aerobic and 171 anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. Antimicrob Agents Chemother. 2003 Sep;47(9):32008-11. 3. Nilius AM, Shen LL, Hensey-Rudloff D, In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone. Antimicrob Agents Chemother. 2003 Oct;47(10):3260-9.

Citations

1. Kong Y, Geng Z, Jiang G, et al.Comparison of the in vitro antibacterial activity of ofloxacin, levofloxacin, moxifloxacin, sitafloxacin, finafloxacin, and delafloxacin against Mycobacterium tuberculosis strains isolated in China.Heliyon.2023

Related compound libraries

This product is contained In the following compound libraries：

EMA Approved Drug Library Inhibitor Library Drug Repurposing Compound Library Immunology/Inflammation Compound Library Bioactive Compound Library FDA-Approved Drug Library Bioactive Compounds Library Max Human Metabolite Library Fluorochemical Library Anti-Bacterial Compound Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Delafloxacin 189279-58-1 Microbiology/Virology Antibacterial Antibiotic RX 3341 ABT492 inhibit WQ 3034 Bacterial ABT 492 RX3341 WQ-3034 Inhibitor WQ3034 ABT-492 RX-3341 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.