keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | Inquiry | $ 1,140.00 |
Description | D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor. |
In vitro | D-JNKI-1 (AM-111; 1μM-1mM) treatment can prevent neomycin-exposed hair cell apoptosis and loss. |
In vivo | D-JNKI-1 (AM-111; 10μM) can prevent almost all hair cell death and permanent hearing loss caused by neomycin ototoxicity in guinea pig cochlea mp. Local delivery of D-JNKI-1 can also prevent permanent hearing loss caused by hearing trauma in a dose-dependent manner. D-JNKI-1 (0.3 mg / kg, intraperitoneal injection) reversed these pathological events in the rat brain mitochondria, almost completely eliminating the release of cytochrome c and the cleavage of PARP. D-JNKI-1 (1 μg / kg, s.c.) caused a significant decrease in the disease activity index and reduced the expression of CD4 + and CD8 + cells in mice. |
Synonyms | XG-102, AM-111 |
Molecular Weight | 3822.44 |
Formula | C164H286N66O40 |
CAS No. | 1445179-97-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 50 mg/mL (13.08 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
D-JNKI-1 1445179-97-4 MAPK JNK D JNKI 1 XG-102 AM 111 AM111 XG102 DJNKI1 AM-111 XG 102 inhibitor inhibit