Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 263.00 | |
5 mg | In stock | $ 648.00 | |
10 mg | In stock | $ 922.00 | |
25 mg | In stock | $ 1,380.00 | |
50 mg | In stock | $ 1,860.00 | |
100 mg | In stock | $ 2,490.00 | |
500 mg | In stock | $ 4,930.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 711.00 |
Description | Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM). |
Targets&IC50 | Chymase:29 nM |
In vitro | Chymase-IN-1 (compound 5f) has a chymase Ki value of 36 nM and a Cat G Ki value of 9500 nM[1]. |
In vivo | Chymase-IN-1 shows low oral bioavailability in rats (F=3%; oral t1/2=1.8 h)[1]. |
Molecular Weight | 431.83 |
Formula | C20H15ClNO4PS |
CAS No. | 862090-74-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (115.79 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Chymase-IN-1 862090-74-2 Others Chymase IN 1 ChymaseIN1 inhibitor inhibit