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BpV(HOpic)

Name: BpV(HOpic)
Brand: TargetMol
SKU: T7953
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7953Cas No. 722494-26-0

Alias bpV (HOpic)

BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).

BpV(HOpic)

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Purity: 99.60%

Catalog No. T7953Alias bpV (HOpic)Cas No. 722494-26-0

BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$39	In Stock	In Stock
5 mg	$89	In Stock	In Stock
10 mg	$143	In Stock	In Stock
25 mg	$288	In Stock	In Stock
50 mg	$432	In Stock	In Stock
100 mg	$626	In Stock	In Stock
200 mg	$883	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.60%

Appearance:Solid

Color:Yellow

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COA LCMS

Product Introduction

Bioactivity

Description	BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).
Targets&IC50	PTEN:14 nM(Cell-free assay)
In vitro	1 μM BpV(Hopic) is capable of enhancing the migration of C2C12 myoblasts by approximately 40 % in the presence of myotube conditioned media, without significantly affecting their capacity to differentiate and fuse into multinucleated myotubes.?Improved migration of myoblasts treated with 1 μM BpV(Hopic) was associated with activation of PI3K/AKT and MAPK/ERK pathways, while their inhibition with either LY294002 or UO126, respectively, resulted in a reduction of C2C12 migration back to control levels[1]
Synonyms	bpV (HOpic)

Chemical Properties

Molecular Weight	347.24
Formula	C₆H₄K₂NO₈V
Cas No.	722494-26-0
Smiles	O=C1[O-][V+3]23([O-][O-]2)([O-][O-]3)([N]4=CC(O)=CC=C14)=O.[K+].[K+]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 58.75 mg/mL (169.19 mM), Sonication is recommended.

DMSO: Insoluble

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.8799 mL	14.3993 mL	28.7985 mL	143.9926 mL
5 mM	0.5760 mL	2.8799 mL	5.7597 mL	28.7985 mL
10 mM	0.2880 mL	1.4399 mL	2.8799 mL	14.3993 mL
20 mM	0.1440 mL	0.7200 mL	1.4399 mL	7.1996 mL
50 mM	0.0576 mL	0.2880 mL	0.5760 mL	2.8799 mL
100 mM	0.0288 mL	0.1440 mL	0.2880 mL	1.4399 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc