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Biotin-PEG2-C2-iodoacetamide

Name: Biotin-PEG2-C2-iodoacetamide
Brand: TargetMol
SKU: T17565
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17565Cas No. 292843-75-5

Alias Biotin-PEG2-iodoacetamide

Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Biotin-PEG2-C2-iodoacetamide

🥰Excellent

Purity: 99.85%

Catalog No. T17565Alias Biotin-PEG2-iodoacetamideCas No. 292843-75-5

Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Pack Size	Price	Availability
5 mg	$38	In Stock
10 mg	$54	In Stock
25 mg	$91	In Stock
50 mg	$148	In Stock
100 mg	$238	In Stock

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Purity:99.85%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
In vitro	PROTACs consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, while the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Synonyms	Biotin-PEG2-iodoacetamide

Chemical Properties

Molecular Weight	542.43
Formula	C₁₈H₃₁IN₄O₅S
Cas No.	292843-75-5
Smiles	C(CCCC(NCCOCCOCCNC(CI)=O)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc