Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Amino-PEG11-amine, a polyethylene glycol (PEG)-based linker with 12 units, facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands. This strategy enhances the preparation of selective and potent estrogen receptor (ER) antagonists, offering an innovative approach for endocrine therapy in breast cancer treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 56.00 | |
25 mg | In stock | $ 87.00 | |
50 mg | In stock | $ 123.00 | |
100 mg | In stock | $ 176.00 |
Description | Amino-PEG11-amine, a polyethylene glycol (PEG)-based linker with 12 units, facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands. This strategy enhances the preparation of selective and potent estrogen receptor (ER) antagonists, offering an innovative approach for endocrine therapy in breast cancer treatment. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 544.68 |
Formula | C24H52N2O11 |
CAS No. | 479200-82-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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Amino-PEG11-amine 479200-82-3 Others PROTAC PROTAC Linker Amino PEG11 amine PROTAC Linkers inhibit Inhibitor Amino-PEG-11-amine AminoPEG11amine inhibitor