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Afamelanotide acetate

Catalog No. T7589 CAS 1566590-77-9

Synonyms: afamelanotide

Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.

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Afamelanotide acetate, CAS 1566590-77-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 97.00
5 mg	In stock	$ 297.00
10 mg	In stock	$ 516.00
25 mg	In stock	$ 898.00
50 mg	In stock	$ 1,188.00
100 mg	In stock	$ 1,782.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.

Synonyms	afamelanotide
Molecular Weight	1706.926
Formula	C80H115N21O21
CAS No.	1566590-77-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Langendonk J G , Balwani M , Anderson K E , et al. Afamelanotide for Erythropoietic Protoporphyria[J]. New England Journal of Medicine, 2015, 373(1):48-59. 2. Kim E S , Garnock-Jones K P . Afamelanotide: A Review in Erythropoietic Protoporphyria[J]. American Journal of Clinical Dermatology, 2016, 17(2):179-185.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Drug Repurposing Compound Library Preclinical Compound Library Anti-Cancer Drug Library Bioactive Compounds Library Max Approved Drug Library Bioactive Compound Library NO PAINS Compound Library Peptide Compound Library Anti-Cancer Approved Drug Library

Related Products

Related compounds with same targets

HS 014 acetate(207678-81-7 free base) HS024 [D-Trp8]-γ-MSH acetate(321351-81-9 free base) Melanotan (MT)-II ACTH 11-24 acetate(4237-93-8 free base) α-MSH Adrenocorticotropic Hormone (ACTH) (4-10), human Bremelanotide Acetate

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Afamelanotide acetate 1566590-77-9 GPCR/G Protein Neuroscience Melanocortin Receptor Melanotan melanotropic peptide skin cancers MC Receptor Melanotan I Inhibitor MC1R α-MSH inhibit MT-I afamelanotide inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.