Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM. AZ13705339 binds PAK2 with a Kd of 0.32 nM. AZ13705339 can be used in studies about cancers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 222.00 | |
50 mg | In stock | $ 355.00 | |
100 mg | In stock | $ 572.00 |
Description | AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM. AZ13705339 binds PAK2 with a Kd of 0.32 nM. AZ13705339 can be used in studies about cancers. |
In vitro | AZ13705339 (300 nM) prevents Siglec-8 binding-induced eosinophil death[2]. In Namalwa cells, AZ13705339 (1 μM) inhibits αIgM-controlled but not PMA-induced adhesion[3]. |
In vivo | In rats, AZ13705339 (100 mg/kg, p.o.) exhibits moderate clearance and Cmax of 7.7 μM[1]. |
Synonyms | AZ-13705339, AZ 13705339 |
Molecular Weight | 629.75 |
Formula | C33H36FN7O3S |
CAS No. | 2016806-57-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225mg/mL (357.3mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AZ13705339 2016806-57-6 Cytoskeletal Signaling PAK AZ-13705339 AZ 13705339 inhibitor inhibit