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(±)-Abscisic acid

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Catalog No. T3014Cas No. 14375-45-2
Alias Dormin, Abscisinsaeure, Abscisic acid

(±)-Abscisic acid is an orally active phytohormone also found in animals. It regulates blood glucose in mammals.

(±)-Abscisic acid

(±)-Abscisic acid

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Purity: 99.87%
Catalog No. T3014Alias Dormin, Abscisinsaeure, Abscisic acidCas No. 14375-45-2
(±)-Abscisic acid is an orally active phytohormone also found in animals. It regulates blood glucose in mammals.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$31In StockIn Stock
25 mg$73In StockIn Stock
50 mg$129In StockIn Stock
100 mg$193-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.87%
Color:White
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Product Introduction

(±)-Abscisic acid AI Summary
(±)-Abscisic acid has been tested across various bioassays demonstrating a broad spectrum of biological activities. Against CYP707A3, it showed 22.0% activity in a rice seedling elongation assay at a concentration of 1 µM. It also inhibited the growth of etiolated wheat coleoptiles in a dose-dependent manner and exhibited strong inhibition in a paper chromatogram assay. Notably, (±)-Abscisic acid acts as an agonist of the Thyroid Stimulating Hormone Receptor with a potency of 31.6 nM and increases intracellular cAMP in HEK 293 cells through the same receptor with the same potency. It also functions as an antagonist of androgen receptor signaling at 631.0 nM and shows agonistic activity against the estrogen receptor alpha pathway at 39810.7 nM. Additionally, it acts on the antioxidant response element (ARE) signaling pathway with a potency of 37578.0 nM and stimulates IL-8 secretion at 74978.0 nM. In inhibition studies, it demonstrated -10.41% activity against electric eel acetylcholinesterase and -4.4% against horse butyrylcholinesterase at 2 mg/ml. Furthermore, it markedly inhibited sodium fluorescein uptake in OATP1B1- and OATP1B3-transfected CHO cells, showing inhibition of 70.85% and 92.91% respectively at a 10 µM concentration, indicating its potential as an inhibitor of these cellular transporters..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
(±)-Abscisic acid is an orally active phytohormone also found in animals. It regulates blood glucose in mammals.
SynonymsDormin, Abscisinsaeure, Abscisic acid
Chemical Properties
Molecular Weight264.32
FormulaC15H20O4
Cas No.14375-45-2
SmilesC\C(C=CC1(O)C(C)=CC(=O)CC1(C)C)=C\C(O)=O
Relative Density.1.193 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 240 mg/mL (907.99 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.57 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7833 mL18.9165 mL37.8329 mL189.1646 mL
5 mM0.7567 mL3.7833 mL7.5666 mL37.8329 mL
10 mM0.3783 mL1.8916 mL3.7833 mL18.9165 mL
20 mM0.1892 mL0.9458 mL1.8916 mL9.4582 mL
50 mM0.0757 mL0.3783 mL0.7567 mL3.7833 mL
100 mM0.0378 mL0.1892 mL0.3783 mL1.8916 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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