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(RS)-Butyryltimolol

Name: (RS)-Butyryltimolol
Brand: TargetMol
SKU: T13439
Rating: 4.5 (1 reviews)

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Catalog No. T13439Cas No. 2320274-78-8

(RS)-Butyryltimolol, the racemate of Butyryltimolol, is an effective prodrug of Timolol that improves corneal penetration and acts as a β-adrenergic blocker [1][2].

(RS)-Butyryltimolol

😃Good

Catalog No. T13439Cas No. 2320274-78-8

(RS)-Butyryltimolol, the racemate of Butyryltimolol, is an effective prodrug of Timolol that improves corneal penetration and acts as a β-adrenergic blocker [1][2].

Pack Size	Price	Availability	Quantity
2 mg	$61	5 days

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Product Introduction

Bioactivity

Description	(RS)-Butyryltimolol, the racemate of Butyryltimolol, is an effective prodrug of Timolol that improves corneal penetration and acts as a β-adrenergic blocker [1][2].
In vitro	Butyryltimolol is a prodrug of Timolol. Butyryltimolol is equally effective as 240-min nasolacrimal blockade in enhancing ocular drug absorption [1].

Chemical Properties

Molecular Weight	386.51
Formula	C₁₇H₃₀N₄O₄S
Cas No.	2320274-78-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (258.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5873 mL	12.9363 mL	25.8726 mL	129.3628 mL
5 mM	0.5175 mL	2.5873 mL	5.1745 mL	25.8726 mL
10 mM	0.2587 mL	1.2936 mL	2.5873 mL	12.9363 mL
20 mM	0.1294 mL	0.6468 mL	1.2936 mL	6.4681 mL
50 mM	0.0517 mL	0.2587 mL	0.5175 mL	2.5873 mL
100 mM	0.0259 mL	0.1294 mL	0.2587 mL	1.2936 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc