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(1S,3R,5R)-PIM447 dihydrochloride

Catalog No. T13425 CAS T13425

Synonyms: (1S,3R,5R)-LGH447 dihydrochloride

(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).

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(1S,3R,5R)-PIM447 dihydrochloride Chemical Structure

(1S,3R,5R)-PIM447 dihydrochloride, CAS T13425

Pack Size	Availability	Price/USD
5 mg	Inquiry	$ 311.00
10 mg	Inquiry	$ 443.00
50 mg	Inquiry	$ 1,323.00
100 mg	Inquiry	Inquiry
200 mg	Inquiry	Inquiry
1 mL * 10 mM (in DMSO)	Inquiry	$ 351.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).
Targets&IC50	Pim1:0.095 μM , Pim1:0.369 μM , Pim1:0.52 μM

Synonyms	(1S,3R,5R)-LGH447 dihydrochloride
Molecular Weight	513.38
Formula	C24H25Cl2F3N4O
CAS No.	T13425

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 33.33 mg/mL (64.92 mM), Sonication is recommended.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

(1S,3R,5R)-PIM447 dihydrochloride T13425 Cell Cycle/Checkpoint CDK (1S,3R,5R)-LGH447 dihydrochloride LGH 447 PIM-447 PIM 447 Dihydrochloride LGH-447 (1S,3R,5R)PIM447 dihydrochloride LGH-447 Dihydrochloride PIM447 Dihydrochloride LGH447 PIM 447 (1S,3R,5R)-PIM-447 dihydrochloride PIM-447 Dihydrochloride PIM447 (1S,3R,5R) PIM447 dihydrochloride LGH 447 Dihydrochloride LGH447 Dihydrochloride inhibitor inhibit

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