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GPCR/G Protein Protease-activated Receptor tcY-NH2 TFA(327177-34-4 free base)

tcY-NH2 TFA(327177-34-4 free base)

Catalog No. TP1925L   CAS TP1925L

tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.

tcY-NH2 TFA(327177-34-4 free base), CAS TP1925L
Pack Size Availability Price/USD Quantity
1 mg In stock 197.00
5 mg In stock 444.00
10 mg In stock 666.00
25 mg In stock 1148.00
50 mg In stock 1797.00
100 mg In stock 2696.00
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Purity 100.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
Targets&IC50
Molecular Weight 853.9
Formula C42H50F3N7O9
CAS No. TP1925L

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Hollenberg et al (2004) Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br.J.Pharmacol. 143 443 PMID: 2. Hollenberg and Saifeddine (2001) Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet aggregation by PAR4-derived peptides. Can.J.Physiol.Pharmacol. 79 439 PMID: 3. Ma et al (2001) Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br.J.Pharmacol. 134 701 PMID:

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