Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ. PI3Kα-IN-7 can reduce cancer cells mitochondrial membrane potential and induce apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ. PI3Kα-IN-7 can reduce cancer cells mitochondrial membrane potential and induce apoptosis. |
In vitro | PI3Kα-IN-7 (Compound A12) demonstrates robust anti-tumor efficacy across various cell lines, including HCT116, PC-3, MCF-7, A549, and MDA-MB-231, with IC50 values of 3.24 μM, 14.37 μM, 7.39 μM, 7.10 μM, and 16.85 μM, respectively [1]. |
Molecular Weight | 402.47 |
Formula | C17H22N8O2S |
CAS No. | 2417098-53-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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PI3Kα-IN-7 2417098-53-2 inhibitor inhibit