Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 8-10 weeks | $ 198.00 | |
5 mg | 8-10 weeks | $ 347.00 | |
25 mg | 8-10 weeks | $ 1,140.00 | |
50 mg | 8-10 weeks | $ 1,490.00 | |
100 mg | 8-10 weeks | $ 1,990.00 | |
1 mL * 10 mM (in DMSO) | 8-10 weeks | $ 382.00 |
Description | p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM). |
Targets&IC50 | p38 MAPK:68 nM |
In vivo | p38 MAPK-IN-1 dose-dependently inhibits TNFα production (ED50: 0.5 mg/kg). p38 MAPK-IN-1 (1 mg/kg for iv and 10 mg/kg for p.o.) has a t1/2 of 7.4 hours and CL of 2.7 mL/min/kg for iv, and a Cmax of 5.3 μM for p.o. in male wistar rats[1]. |
Molecular Weight | 348.35 |
Formula | C21H14F2N2O |
CAS No. | 1006378-90-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8.33 mg/mL (23.84 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
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