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Eg5 Inhibitor V, trans-24

Name: Eg5 Inhibitor V, trans-24
Brand: TargetMol
SKU: T11155
Price: 77 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11155Cas No. 869304-55-2

Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.

Eg5 Inhibitor V, trans-24

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Purity: 99.75%

Catalog No. T11155Cas No. 869304-55-2

Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$77	In Stock	In Stock
5 mg	$176	In Stock	In Stock
10 mg	$263	In Stock	In Stock
25 mg	$430	In Stock	In Stock
50 mg	$623	In Stock	In Stock
100 mg	$878	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$198	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.75%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.
Targets&IC50	EG5:0.65 μM
In vitro	Trans-24 is a potent EG5-specific inhibitor with an IC50 conversion rate of 0.65 M and can be used in cancer research[1].

Chemical Properties

Molecular Weight	423.46
Formula	C₂₆H₂₁N₃O₃
Cas No.	869304-55-2
Smiles	[H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(Cc1ccccc1)C2=O)c1cccc(O)c1
Relative Density.	1.47 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (106.27 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3615 mL	11.8075 mL	23.6150 mL	118.0749 mL
5 mM	0.4723 mL	2.3615 mL	4.7230 mL	23.6150 mL
10 mM	0.2361 mL	1.1807 mL	2.3615 mL	11.8075 mL
20 mM	0.1181 mL	0.5904 mL	1.1807 mL	5.9037 mL
50 mM	0.0472 mL	0.2361 mL	0.4723 mL	2.3615 mL
100 mM	0.0236 mL	0.1181 mL	0.2361 mL	1.1807 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc