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Angiotensin III, human, mouse

Name: Angiotensin III, human, mouse
Brand: TargetMol
SKU: T7577
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7577Cas No. 13602-53-4

Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).

Angiotensin III, human, mouse

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Purity: 98.44%

Catalog No. T7577Cas No. 13602-53-4

Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$48	In Stock	In Stock
25 mg	$91	In Stock	In Stock
50 mg	$153	In Stock	In Stock
100 mg	$249	In Stock	In Stock
200 mg	$375	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.44%

Appearance:Solid

Color:White

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COA LCMS

Product Introduction

Bioactivity

Description	Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
Targets&IC50	Ang II receptor:0.648 nM
In vivo	Angiotensin III, human, mouse increased urine sodium excretion, fractional sodium, and lithium excretion.?RI coinfusion of specific angiotensin type 2 receptor antagonist PD-123319 abolished Ang III-induced natriuresis[1].

Chemical Properties

Molecular Weight	931.09
Formula	C₄₆H₆₆N₁₂O₉
Cas No.	13602-53-4
Smiles	C([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)[C@@H](C)C)=O)=O)[C@H](CC)C)=O)(=O)N3[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CCC3
Relative Density.	1.39g/cm3
Sequence	Arg-Val-Tyr-Ile-His-Pro-Phe
Sequence Short	RVYIHPF

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 127.5 mg/mL (136.94 mM), Sonication is recommended.

DMSO: 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.0740 mL	5.3701 mL	10.7401 mL	53.7005 mL
5 mM	0.2148 mL	1.0740 mL	2.1480 mL	10.7401 mL
10 mM	0.1074 mL	0.5370 mL	1.0740 mL	5.3701 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.0537 mL	0.2685 mL	0.5370 mL	2.6850 mL
50 mM	0.0215 mL	0.1074 mL	0.2148 mL	1.0740 mL
100 mM	0.0107 mL	0.0537 mL	0.1074 mL	0.5370 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc