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9-Cyclopentyladenine

Name: 9-Cyclopentyladenine
Brand: TargetMol
SKU: T29652
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T29652Cas No. 715-91-3

Alias NSC-19486, NSC19486, NSC 19486, 9-CP-Ade, 9CPAde, 9 CP Ade

9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.

9-Cyclopentyladenine

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Purity: 99.98%

Catalog No. T29652Alias NSC-19486, NSC19486, NSC 19486, 9-CP-Ade, 9CPAde, 9 CP AdeCas No. 715-91-3

9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
5 mg	$430	In Stock	In Stock
10 mg	$636	In Stock	In Stock
25 mg	$987	In Stock	In Stock
50 mg	$1,360	In Stock	In Stock
100 mg	$1,830	-	In Stock
500 mg	$3,680	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

9-Cyclopentyladenine AI Summary

9-Cyclopentyladenine exhibits inhibitory activity against human phosphatidylinositol 4-kinase at the ATP binding site with an IC50 value of 8700.0 nM and shows binding affinity with a Ki value of 6000.0 nM. It has notable binding affinities for various adenosine receptors: a Ki value of 1800.0 nM for the adenosine A1 receptor in rat cortex, 8200.0 nM for the adenosine A2 receptor in rat striatum, a Ki value of 10000.0 nM for the human adenosine A1 receptor, 1800.0 nM for the adenosine A2A receptor, above 30000.0 nM for the adenosine A2B receptor, and 13000.0 nM for the adenosine A3 receptor. It inhibits rat PC12 adenylate cyclase stimulation with a Ki value of 3400.0 nM and has a hydrophobicity index of k' = 1.94 with a selectivity ratio of 4.6 for the adenosine A1 to A2 receptor. Additionally, 9-Cyclopentyladenine demonstrates antibacterial activity against several bacterial strains, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, with MICs ranging from 25.0 to 50.0 µg/mL. It also exhibits antifungal activity against Candida albicans with an MIC of 12.5 µg/mL and displays antiplasmodial activity against Plasmodium falciparum 3D7 with an IC50 value of 7943.28 nM. Furthermore, this compound shows bioactivities related to genotoxicity induction in human embryonic kidney cells (2310.0 nM), inhibition of Histone Lysine Methyltransferase G9a (29934.9 nM), inhibition of T. brucei phosphofructokinase (12.0 nM), and inhibition of binding or entry into cells by Marburg Virus (6309.6 nM)..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling molecules.
Synonyms	NSC-19486, NSC19486, NSC 19486, 9-CP-Ade, 9CPAde, 9 CP Ade

Chemical Properties

Molecular Weight	203.24
Formula	C₁₀H₁₃N₅
Cas No.	715-91-3
Smiles	NC1=C2C(N(C=N2)C3CCCC3)=NC=N1
Relative Density.	1.56g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (246.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.9203 mL	24.6015 mL	49.2029 mL	246.0146 mL
5 mM	0.9841 mL	4.9203 mL	9.8406 mL	49.2029 mL
10 mM	0.4920 mL	2.4601 mL	4.9203 mL	24.6015 mL
20 mM	0.2460 mL	1.2301 mL	2.4601 mL	12.3007 mL
50 mM	0.0984 mL	0.4920 mL	0.9841 mL	4.9203 mL
100 mM	0.0492 mL	0.2460 mL	0.4920 mL	2.4601 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc