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ZD 7155(hydrochloride)

Catalog No. T13390 CAS 146709-78-6

ZD 7155 hydrochloride is an antagonist of angiotensin II receptor type 1 (AT1 receptor).

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ZD 7155(hydrochloride), CAS 146709-78-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	ZD 7155 hydrochloride is an antagonist of angiotensin II receptor type 1 (AT1 receptor).
In vivo	ZD 7155 and losartan behave as competitive antagonists and the pressor response curve to angiotensin II is shifted to the right in conscious SD rats. Experiments in conscious SD rats also show that ZD 7155 is approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response (240 ng/kg; 10 min infusion).

Molecular Weight	474.99
Formula	C26H27ClN6O
CAS No.	146709-78-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Junggren IL, et al. Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat. J Pharm Pharmacol. 1996 Aug;48(8):829-33.

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Keywords

ZD 7155(hydrochloride) 146709-78-6 DNA损伤和修复代谢细胞周期 DHFR Inhibitor inhibitor inhibit

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