Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC926 (UNC-926) inhibits L3MBTL1 (IC50: 3.9 μM). UNC926 also exhibits a low micromolar affinity for L3MBTL3. UNC926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC926 has not an effect on the binding of 53BP1 to H4K20me1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 46.00 | |
10 mg | In stock | $ 79.00 | |
25 mg | In stock | $ 155.00 | |
50 mg | In stock | $ 278.00 | |
100 mg | In stock | $ 448.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 51.00 |
Description | UNC926 (UNC-926) inhibits L3MBTL1 (IC50: 3.9 μM). UNC926 also exhibits a low micromolar affinity for L3MBTL3. UNC926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC926 has not an effect on the binding of 53BP1 to H4K20me1. |
Targets&IC50 | L3MBTL1:3.9 μM(Kd) |
Synonyms | UNC-926, UNC 926 hydrochloride |
Molecular Weight | 337.25 |
Formula | C16H21BrN2O |
CAS No. | 1184136-10-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 37.4 mg/mL(100 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
UNC926 1184136-10-4 Chromatin/Epigenetic Epigenetic Reader Domain 3xMBT L3MBTL1 methyl-lysine UNC 926 Hydrochloride H4K20me1 Inhibitor UNC-926 Hydrochloride L3MBTL3 inhibit UNC-926 UNC926 Hydrochloride UNC 926 UNC 926 hydrochloride inhibitor